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Protein Coding Gene : Tssk4 testis-specific serine kinase 4
Primary Identifier  MGI:1918349 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  71099
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables magnesium ion binding activity; protein homodimerization activity; and protein serine/threonine kinase activity. Involved in several processes, including flagellated sperm motility; positive regulation of CREB transcription factor activity; and protein phosphorylation. Located in sperm flagellum. Orthologous to human TSSK4 (testis specific serine kinase 4).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced male fertility, decreased sperm ferility and abnormal axoneme structure and sperm midpiece morphology. [provided by MGI curators]
  • synonyms:
  • 4933424F08Rik,
  • RIKEN cDNA 1700020B19 gene,
  • 1700020B19Rik,
  • testis-specific serine kinase 4,
  • RIKEN cDNA 4933424F08 gene,
  • MGI:1923651,
  • Tssk4
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