Primary Identifier | MGI:1888501 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 57260 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables leukotriene B4 receptor activity. Acts upstream of or within keratinocyte migration and signal transduction. Located in membrane. Orthologous to human LTB4R2 (leukotriene B4 receptor 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced incidence and severity of autoantibody-induced inflammatory arthritis and decreased susceptibility to IgE antigen-dependent passive cutaneous anaphylaxis. [provided by MGI curators] |