| Primary Identifier | MGI:1309472 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 16995 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables leukotriene B4 receptor activity. Acts upstream of or within signal transduction. Predicted to be active in plasma membrane. Is expressed in brain and lateral ventricle. Orthologous to human LTB4R (leukotriene B4 receptor). PHENOTYPE: Nullizygous mutations cause impaired Ltb4-driven chemotaxis and adhesion. Homozygous null phenotypes include attenuated autoAb-driven arthritis, adoptive transfer-induced uveitis, airway hyperresponsiveness and Th2-type immune responses, and reduced eosinophil recruitment in induced peritonitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
