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Protein Coding Gene : Gzmc granzyme C
Primary Identifier  MGI:109256 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  14940
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in several processes, including granzyme-mediated programmed cell death signaling pathway; natural killer cell mediated cytotoxicity; and pyroptotic inflammatory response. Predicted to be located in cytolytic granule. Predicted to be active in cytoplasm and extracellular space. Is expressed in extraembryonic component; placenta; spongiotrophoblast; and trophoblast giant cell. Orthologous to human GZMB (granzyme B).
  • synonyms:
  • MGD-MRK-2235,
  • expressed sequence AI323531,
  • MGD-MRK-38301,
  • MGI:2145616,
  • AI323531,
  • cytotoxic T lymphocyte-associated protein 5,
  • Ctla5,
  • CCP2,
  • granzyme C,
  • Gzmc,
  • Ctla-5
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Features --> Cross References

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1 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

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Mouse features --> Functions (GO terms)

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Disease

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