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Protein Coding Gene : Shisa2 shisa family member 2
Primary Identifier  MGI:2444716 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  219134
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within negative regulation of Wnt signaling pathway and negative regulation of fibroblast growth factor receptor signaling pathway. Located in endoplasmic reticulum. Is expressed in several structures, including embryo ectoderm; embryo mesenchyme; gut; primitive endoderm; and sensory organ. Orthologous to human SHISA2 (shisa family member 2).
PHENOTYPE: Mice homozygous for a null alle exhibit dwarfism, delayed growth and postnatal lethality with abnormal hypothalamus morphology. [provided by MGI curators]
  • synonyms:
  • 9430059P22Rik,
  • MAd2,
  • transmembrane protein 46,
  • RIKEN cDNA 9430059P22 gene,
  • shisa family member 2,
  • Tmem46,
  • Shisa2,
  • mShisa,
  • shisa
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