Primary Identifier | MGI:3045252 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 239126 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables hormone activity and identical protein binding activity. Acts upstream of or within several processes, including negative regulation of cell size; positive regulation of cellular response to insulin stimulus; and positive regulation of protein serine/threonine kinase activity. Located in extracellular space. Is expressed in several structures, including adipose tissue; genitourinary system; hemolymphoid system; liver; and musculature. Orthologous to human C1QTNF9 (C1q and TNF related 9) and C1QTNF9B (C1q and TNF related 9B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased caloric intake, increased percent body fat/body weight, obesity, insulin resistance, and hepatic steatosis. [provided by MGI curators] |