Primary Identifier | MGI:1352474 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 29820 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable signaling receptor activity. Acts upstream of or within hair follicle development and positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; integumental system; and respiratory system. Orthologous to human TNFRSF19 (TNF receptor superfamily member 19). PHENOTYPE: Homozygous mutant mice exhibit no obvious physical abnormalities or alterations in behavior, locomotion, or fecundity, however neurons are more resistant to the suppressive action of myelin inhibitors. [provided by MGI curators] |