Primary Identifier | MGI:1913847 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 66597 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription coactivator activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including defense response to symbiont; negative regulation of viral transcription; and proteasomal protein catabolic process. Located in cytoplasm. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; and thymus. Orthologous to human TRIM13 (tripartite motif containing 13). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased lethality induced by EMCV infection and altered type I IFN production. [provided by MGI curators] |