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Protein Coding Gene : Hmbox1 homeobox containing 1
Primary Identifier  MGI:2445066 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  219150
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables telomeric DNA binding activity. Involved in telomere maintenance via telomerase. Located in chromosome, telomeric region and nucleus. Is expressed in several structures, including central nervous system; early conceptus; female reproductive system; limb mesenchyme; and urinary system. Orthologous to human HMBOX1 (homeobox containing 1).
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit absence of TERT binding to chromatin as shown by subcellular fractionation analysis of mouse embryonic fibroblasts. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI451877,
  • F830020C16Rik,
  • expressed sequence AI604847,
  • AI451877,
  • MGI:2145678,
  • RIKEN cDNA F830020C16 gene,
  • homeobox containing 1,
  • MGI:2145656,
  • Hmbox1,
  • AI604847
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Features --> Cross References

Genome

Sequence Feature Displayer

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1 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

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Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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Literature

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