Primary Identifier | MGI:1921445 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 74195 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphorylase kinase regulator activity and tRNA uridine(34) acetyltransferase activity. Involved in central nervous system development; neuron migration; and positive regulation of cell migration. Predicted to be located in cytosol and nucleolus. Predicted to be part of elongator holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in brain. Orthologous to human ELP3 (elongator acetyltransferase complex subunit 3). PHENOTYPE: Embryos homozygous for a null gene trap mutation show severe growth retardation and die prior to E12.5. [provided by MGI curators] |