| Primary Identifier | MGI:2685446 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 100503545 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activity. Acts upstream of or within DNA damage response and somatic hypermutation of immunoglobulin genes. Located in nucleus. Orthologous to human NUGGC (nuclear GTPase, germinal center associated). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased somatic mutation frequency immunoglobulin and non-immunoglobulin loci in B cells. [provided by MGI curators] |