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Protein Coding Gene : Trim35 tripartite motif-containing 35

Primary Identifier  MGI:1914104 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  66854
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within negative regulation of cell population proliferation and positive regulation of myeloid cell apoptotic process. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; lung; and sensory organ. Orthologous to human TRIM35 (tripartite motif containing 35).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased serum interferon-beta levels in response to vesicular stomatitis virus infection and show increased susceptibility to influenza A virus infection. [provided by MGI curators]
  • synonyms:
  • MGI:2145786,
  • RIKEN cDNA A430106H13 gene,
  • 0710005M05Rik,
  • AW046487,
  • MGI:1925036,
  • Hls5,
  • expressed sequence AW046487,
  • Trim35,
  • tripartite motif-containing 35,
  • mKIAA1098,
  • RIKEN cDNA 0710005M05 gene,
  • A430106H13Rik,
  • Mair

Features --> Cross References

Genome

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1 Involved In Mutations

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0 Transgenic Expressors

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

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