| Primary Identifier | MGI:104773 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 11549 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables alpha1-adrenergic receptor activity. Involved in several processes, including neuron-glial cell signaling; pilomotor reflex; and positive regulation of smooth muscle contraction. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; heart development; and regulation of systemic arterial blood pressure. Located in membrane. Is expressed in several structures, including brain and heart. Human ortholog(s) of this gene implicated in Alzheimer's disease; heroin dependence; and hypertension. Orthologous to human ADRA1A (adrenoceptor alpha 1A). PHENOTYPE: Mutations in this gene result in hypotension. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
