Primary Identifier | MGI:1919228 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 71978 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables enzyme-substrate adaptor activity and protein phosphatase regulator activity. Involved in regulation of chromosome segregation. Acts upstream of or within response to morphine. Part of protein phosphatase type 2A complex. Is active in glutamatergic synapse. Is expressed in eye. Orthologous to human PPP2R2A (protein phosphatase 2 regulatory subunit Balpha). PHENOTYPE: Mice heterozygous for an ENU-induced hypomorphic allele exhibit increased circulating insulin level and pancreatic beta cell mas and insulin resistance. [provided by MGI curators] |