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Protein Coding Gene : Adamdec1 ADAM-like, decysin 1
Primary Identifier  MGI:1917650 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  58860
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Is expressed in foregut-midgut junction; hindgut; large intestine; midgut; and stomach. Orthologous to human ADAMDEC1 (ADAM like decysin 1).
PHENOTYPE: Mice homozygous for a null allele are more susceptible to the induction of bacterial and chemical induced colitis, showing more weight loss, increased mortality, increased neutrophil infiltration and greater IL-6 and Il-1beta secretion. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2210414L24 gene,
  • Dcsn,
  • decysin,
  • AI574231,
  • expressed sequence AI574231,
  • 2210414L24Rik,
  • ADAM-like, decysin 1,
  • Adamdec1,
  • MGI:2145672
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1 Involved In Mutations

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