| Primary Identifier | MGI:1914962 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 67712 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ferrous iron transmembrane transporter activity. Involved in iron import into the mitochondrion and positive regulation of hemoglobin biosynthetic process. Located in mitochondrial inner membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; immune system; and retina nuclear layer. Orthologous to human SLC25A37 (solute carrier family 25 member 37). PHENOTYPE: Embryos homozygous for a knock-out allele are pale, exhibit no hemoglobinization in the yolk sac and heart, and die during organogenesis. Homozygous hepatocyte specific KO affects iron metabolism and oxidative phosphorylation in liver mitochondria leads to a reduction of liver regeneration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
