| Primary Identifier | MGI:1306780 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 13655 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within neuromuscular synaptic transmission; peripheral nervous system development; and regulation of T cell differentiation. Predicted to be located in nucleoplasm. Is expressed in several structures, including ganglionic eminence; genitourinary system; limb musculature; tooth; and vibrissa. Orthologous to human EGR3 (early growth response 3). PHENOTYPE: Homozygous null mutants exhibit partial postnatal lethality, sensory ataxia, resting tremors, blepharoptosis, scoliosis, muscle spindle agenesis, loss of myelinated proprioceptive neurons, and a defect in the strength of sensory-motor connections. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
