Primary Identifier | MGI:1332623 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 13449 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transmembrane receptor protein tyrosine kinase adaptor activity. Acts upstream of or within Ras protein signal transduction and cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; immune system; liver; and lung. Orthologous to human DOK2 (docking protein 2). PHENOTYPE: Homozygous null mice display abnormal granulocyte physiology. [provided by MGI curators] |