| Primary Identifier | MGI:1195462 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 14586 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable glial cell-derived neurotrophic factor receptor activity and heparan sulfate binding activity. Acts upstream of or within cell surface receptor protein tyrosine kinase signaling pathway and nervous system development. Predicted to be located in plasma membrane and side of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and skin. Orthologous to human GFRA2 (GDNF family receptor alpha 2). PHENOTYPE: Homozygous mutants have dry eyes, poor postweaning growth associated with impaired parasympathetic cholinergic innervation of lacrimal and salivary glands and of small intestine, reduced skin thickness and accelerated hair follicle regression. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
