| Primary Identifier | MGI:1917336 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 70086 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cysteinyl leukotriene receptor activity. Predicted to be involved in several processes, including negative regulation of glial cell proliferation; neuropeptide signaling pathway; and positive regulation of ERK1 and ERK2 cascade. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Located in membrane. Human ortholog(s) of this gene implicated in aspirin-induced respiratory disease and asthma. Orthologous to human CYSLTR2 (cysteinyl leukotriene receptor 2). PHENOTYPE: Homozygous null mice display reduced bleomycin-induced pulmonary fibrosis and reduced IgE dependent passive cutaneous anaphylaxis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
