| Primary Identifier | MGI:1891837 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 56373 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables carboxypeptidase activity. Predicted to be involved in several processes, including negative regulation of hepatocyte proliferation; negative regulation of plasminogen activation; and regulation of blood coagulation. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; liver; and skeleton. Human ortholog(s) of this gene implicated in chronic kidney disease. Orthologous to human CPB2 (carboxypeptidase B2). PHENOTYPE: Homozygous null mice exhibit altered plasma clot lysis and may show reduced bleomycin-induced lung fibrosis, impaired healing of cutaneous wounds and colonic anastomoses, altered glomerular structure, or complement-mediated lethal inflammation after LPS sensitization. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
