| Primary Identifier | MGI:2445077 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 210808 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable adenosine deaminase activity; copper ion binding activity; and pentosyltransferase activity. Involved in regulation of inflammatory response and regulation of purine nucleotide metabolic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in juvenile rheumatoid arthritis. Orthologous to human LACC1 (laccase domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased fatty acid oxidation and glycolysis in macrophages and increased susceptibility to LPS-induced endotoxin shock. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
