Primary Identifier | MGI:1913398 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 66148 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATPase activator activity. Acts upstream of or within several processes, including cellular response to starvation; negative regulation of mitochondrial electron transport, NADH to ubiquinone; and negative regulation of protein-containing complex assembly. Located in mitochondrial inner membrane. Is expressed in endocrine gland; genitourinary system; heart; and nervous system. Orthologous to human DNAJC15 (DnaJ heat shock protein family (Hsp40) member C15). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased mitochondrial activity that results in rapid metabolism in fasted mice or mice fed a high fat diet. [provided by MGI curators] |