| Primary Identifier | MGI:1915168 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 108670 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to lipopolysaccharide; cellular response to type II interferon; and macrophage differentiation. Is expressed in central nervous system; retina; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human EPSTI1 (epithelial stromal interaction 1). PHENOTYPE: Mice homozygous for a null allele exhibit enhanced M2 macrophage differentiation and inhibited M1 polarization. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
