Primary Identifier | MGI:2444188 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 380921 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP-dependent diacylglycerol kinase activity. Involved in diacylglycerol metabolic process; lipid phosphorylation; and phosphatidic acid biosynthetic process. Located in actin cytoskeleton; cytoplasm; and plasma membrane. Is expressed in nervous system and neural retina. Orthologous to human DGKH (diacylglycerol kinase eta). PHENOTYPE: Mice homozygous for a null allele exhibit hyperactivity, decreased anxiety-related behaviors, and impaired spatial learning and memory. [provided by MGI curators] |