| Primary Identifier | MGI:2684924 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 219228 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in synaptic membrane adhesion. Acts upstream of or within several processes, including negative regulation of synaptic transmission; presynaptic active zone assembly; and regulation of synaptic vesicle clustering. Is active in GABA-ergic synapse; glutamatergic synapse; and synaptic membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PCDH17 (protocadherin 17). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired synaptic transmission, increased synaptic vesicle number and decreased depression-related behavior. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
