| Primary Identifier | MGI:1261910 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 52023 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable interleukin-4 receptor binding activity. Predicted to be involved in several processes, including mitotic sister chromatid segregation; regulation of biosynthetic process; and regulation of protein phosphorylation. Predicted to be located in centriolar satellite; extracellular space; and nucleus. Predicted to be active in microtubule organizing center. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Human ortholog(s) of this gene implicated in Joubert syndrome 33. Orthologous to human PIBF1 (progesterone immunomodulatory binding factor 1). PHENOTYPE: Mice homozygous for a knock-out allele show pericardial edema, abnormal heart looping, absence of embryonic cilia, and complete embryonic lethality prior to organogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
