| Primary Identifier | MGI:2443198 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 239250 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including auditory behavior; linear vestibuloocular reflex; and nervous system development. Located in cell periphery. Is expressed in several structures, including brain; gut; limb bud; lung; and sensory organ. Used to study high myopia-sensorineural deafness syndrome and sensorineural hearing loss. Human ortholog(s) of this gene implicated in high myopia-sensorineural deafness syndrome. Orthologous to human SLITRK6 (SLIT and NTRK like family member 6). PHENOTYPE: Homozygous deficient mice show pronounced reduction in cochlear innervation. Innervation to the posterior crista is variably impaired and a there is a loss of neurons in the spiral and vestibular ganglia. Retinas exhibit delayed synaptogenesis and myopia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
