Primary Identifier | MGI:2679448 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 75409 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission. Acts upstream of or within several processes, including grooming behavior; neuron projection morphogenesis; and positive regulation of synapse assembly. Is active in postsynaptic density membrane. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and neural retina. Orthologous to human SLITRK5 (SLIT and NTRK like family member 5). PHENOTYPE: Mice homozygous for a null allele have abnormal medium spiny neuron morphology and exhibit behavioral abnormalities. [provided by MGI curators] |