Primary Identifier | MGI:2385007 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 223255 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway in response to oxidative stress; positive regulation of axon regeneration; and protein autophosphorylation. Predicted to be located in Golgi membrane; cytosol; and nucleolus. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in Golgi apparatus. Is expressed in central nervous system and neural retina. Orthologous to human STK24 (serine/threonine kinase 24). PHENOTYPE: A hypomorphic mutation increases degranulation of, and exocytosis by, neutrophils. [provided by MGI curators] |