| Primary Identifier | MGI:109189 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 14169 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable growth factor activity; heparin binding activity; and sodium channel regulator activity. Acts upstream of or within several processes, including adult locomotory behavior; neuromuscular process; and positive regulation of sodium ion transport. Located in cytosol and nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; respiratory system; and sensory organ. Used to study Alzheimer's disease; frontotemporal dementia; and spinocerebellar ataxia type 27. Human ortholog(s) of this gene implicated in autosomal dominant cerebellar ataxia. Orthologous to human FGF14 (fibroblast growth factor 14). PHENOTYPE: Mice homozygous for disruptions in this gene display impaired balance and grip strength. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
