Primary Identifier | MGI:894288 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 20363 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables selenium binding activity. Acts upstream of or within several processes, including brain development; locomotory behavior; and selenium compound metabolic process. Located in extracellular space. Is expressed in several structures, including central nervous system; embryo mesenchyme; extraembryonic component; genitourinary system; and integumental system. Orthologous to human SELENOP (selenoprotein P). PHENOTYPE: Homozygotes for targeted null mutations exhibit ataxia, spasticity, impaired growth, reduced male fertility, and excess mortality. [provided by MGI curators] |