| Primary Identifier | MGI:3032959 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 239319 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to act upstream of or within regulation of canonical NF-kappaB signal transduction. Predicted to be located in cytoplasm. Is expressed in heart ventricle; lung; upper arm muscle; upper leg muscle; and vertebral axis musculature. Orthologous to human CARD6 (caspase recruitment domain family member 6). PHENOTYPE: Knockout mice are viable and grossly normal with no deficits in thymocytes, granulocytes, macrophages, NK cells or T- and B-cell subsets. Various signaling pathways mediating innate and adaptive immune responses appear unaltered. Mice are normally resistant to infection by a wide range of pathogens. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
