| Primary Identifier | MGI:1926007 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 78757 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ribosome binding activity. Involved in several processes, including TORC2 signaling; regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of protein phosphorylation. Acts upstream of or within several processes, including positive regulation of actin filament polymerization; regulation of establishment of cell polarity; and regulation of protein phosphorylation. Part of TORC2 complex. Is expressed in early conceptus; embryo; and oocyte. Human ortholog(s) of this gene implicated in breast ductal carcinoma; gastrointestinal system cancer (multiple); and lung cancer (multiple). Orthologous to human RICTOR (RPTOR independent companion of MTOR complex 2). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality during organogenesis associated with abnormal placental morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
