Primary Identifier | MGI:1932136 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 81799 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in positive regulation of adiponectin secretion and positive regulation of cytokine production. Acts upstream of or within glucose homeostasis; negative regulation of gluconeogenesis; and positive regulation of intracellular signal transduction. Located in extracellular space. Part of protein-containing complex. Is expressed in several structures, including central nervous system; epithelium; jaw; metanephros; and musculoskeletal system. Orthologous to human C1QTNF3 (C1q and TNF related 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to collagen-induced arthritis. [provided by MGI curators] |