| Primary Identifier | MGI:2146046 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 239337 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metalloendopeptidase activity. Involved in collagen fibril organization; proteoglycan metabolic process; and skeletal system development. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Is expressed in several structures, including lip; meninges; skeleton; spinal cord floor plate; and submandibular gland primordium. Orthologous to human ADAMTS12 (ADAM metallopeptidase with thrombospondin type 1 motif 12). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased tumor vascularization, tumor invasion, and angiogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
