Primary Identifier | MGI:2442458 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 239364 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in several processes, including cellular response to gamma radiation; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and positive regulation of protein ubiquitination. Predicted to be located in chromatin. Predicted to be active in nucleus. Orthologous to human TSPYL5 (TSPY like 5). PHENOTYPE: Homozygous null males show reduced fertility with age, with reduced spermatogonia and sperm counts, reduced spermatogonia proliferation, and abnormal seminiferous tubule morphology. [provided by MGI curators] |