| Primary Identifier | MGI:1914404 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 67154 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable NF-kappaB binding activity; double-stranded RNA binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of intracellular signal transduction; and regulation of DNA-templated transcription. Located in endoplasmic reticulum membrane; nucleolus; and perinuclear region of cytoplasm. Is expressed in several structures, including brain; genitourinary system; limb primordium; nose; and skin. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human MTDH (metadherin). PHENOTYPE: Mice homozygous for a null allele are viable and fertile with decreased incidence of tumors by chemical induction. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
