| Primary Identifier | MGI:1928487 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 56274 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP binding activity; magnesium ion binding activity; and transcription regulator activator activity. Involved in hippo signaling. Acts upstream of or within several processes, including chordate embryonic development; hepatocyte apoptotic process; and regulation of signal transduction. Located in cytoplasm. Is expressed in cerebral cortex; genitourinary system; and lung. Orthologous to human STK3 (serine/threonine kinase 3). PHENOTYPE: Homozygous inactivation of this gene generally results in mice that are viable, fertile and developmentally normal. A small subset of mice homozygous for a knock-out allele develop mammary tumors in the absence of immunological defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
