| Primary Identifier | MGI:108474 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 14368 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables Wnt-protein binding activity. Acts upstream of or within several processes, including cell proliferation in midbrain; embryonic morphogenesis; and establishment of body hair planar orientation. Located in apical plasma membrane; apicolateral plasma membrane; and endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 1. Orthologous to human FZD6 (frizzled class receptor 6). PHENOTYPE: Homozygous mice display abnormal hair follicle orientation and hair growth pattern. Homozygosity for the p.S354I mutation leads to misorientation of just posterior hair follicles. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
