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Protein Coding Gene : Tmem74 transmembrane protein 74
Primary Identifier  MGI:2443417 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  239408
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables transmembrane transporter binding activity. Acts upstream of or within general adaptation syndrome, behavioral process and regulation of cation channel activity. Located in plasma membrane. Is expressed in cerebral cortex subventricular zone and cortical plate. Orthologous to human TMEM74 (transmembrane protein 74).
PHENOTYPE: Homozygous knockout affects basolateral amygdaloid nucleus (BLA) pyramidal neuron electrophysiology, leading to increased anxiety-like behavior. [provided by MGI curators]
  • synonyms:
  • transmembrane protein 74,
  • expressed sequence AA549547,
  • AA549547,
  • RIKEN cDNA B230382K22 gene,
  • Tmem74,
  • B230382K22Rik,
  • MGI:3034807
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