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Protein Coding Gene : Med30 mediator complex subunit 30
Primary Identifier  MGI:1917040 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  69790
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable nuclear thyroid hormone receptor binding activity and transcription coactivator activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within somatic stem cell population maintenance. Part of mediator complex. Is expressed in several structures, including branchial arch; limb; limb bud; tongue; and trunk somite. Orthologous to human MED30 (mediator complex subunit 30).
PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit premature death associated with cachexia and a rapidly progressive cardiomyopathy. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1810038N03 gene,
  • MGI:1917553,
  • Thrap6,
  • 2510044J04Rik,
  • mediator complex subunit 30,
  • RIKEN cDNA 2510044J04 gene,
  • 1810038N03Rik,
  • Trap25,
  • thyroid hormone receptor associated protein 6,
  • Med30
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3 Involved In Mutations

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