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Protein Coding Gene : Deptor DEP domain containing MTOR-interacting protein

Primary Identifier  MGI:2146322 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  97998
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable GTPase regulator activity; phosphatidic acid binding activity; and protein serine/threonine kinase inhibitor activity. Predicted to be involved in several processes, including negative regulation of TOR signaling; negative regulation of cell size; and negative regulation of protein kinase activity. Predicted to be active in lysosomal membrane and plasma membrane. Is expressed in brain and lung. Orthologous to human DEPTOR (DEP domain containing MTOR interacting protein).
PHENOTYPE: Homozygous conditional KO in the liver results in lower hepatic glycogen content and increased oxidative metabolism in fasted mice. [provided by MGI curators]
  • synonyms:
  • DNA segment, Chr 15, ERATO Doi 597, expressed,
  • MGI:1918827,
  • DNA segment, Chr 15, ERATO Doi 336, expressed,
  • MGI:1289169,
  • RIKEN cDNA 4731402B04 gene,
  • D15Ertd597e,
  • R75183,
  • Deptor,
  • 9130412E02Rik,
  • expressed sequence R75183,
  • MGI:1921823,
  • Depdc6,
  • DEP domain containing MTOR-interacting protein,
  • 4731402B04Rik,
  • RIKEN cDNA 9130412E02 gene,
  • D15Ertd336e,
  • DEP domain containing 6,
  • MGI:1196436

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0 Canonical

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4 Involved In Mutations

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2 Transgenic Expressors

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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