Primary Identifier | MGI:2146322 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 97998 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase regulator activity; phosphatidic acid binding activity; and protein serine/threonine kinase inhibitor activity. Predicted to be involved in several processes, including negative regulation of TOR signaling; negative regulation of cell size; and negative regulation of protein kinase activity. Predicted to be active in lysosomal membrane and plasma membrane. Is expressed in brain and lung. Orthologous to human DEPTOR (DEP domain containing MTOR interacting protein). PHENOTYPE: Homozygous conditional KO in the liver results in lower hepatic glycogen content and increased oxidative metabolism in fasted mice. [provided by MGI curators] |