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Protein Coding Gene : Mtbp Mdm2, transformed 3T3 cell double minute p53 binding protein

Primary Identifier  MGI:2146005 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  105837
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within negative regulation of cell population proliferation; negative regulation of mitotic nuclear division; and traversing start control point of mitotic cell cycle. Located in kinetochore. Is expressed in cerebellum; cerebral cortex subventricular zone; midbrain ventricular layer; olfactory cortex ventricular layer; and telencephalon ventricular layer. Orthologous to human MTBP (MDM2 binding protein).
PHENOTYPE: Mice homozygous for a reporter allele exhibit early embryonic lethality; interestingly, heterozygous mice are not tumor prone. [provided by MGI curators]
  • synonyms:
  • MDM2BP,
  • expressed sequence AI429604,
  • AI429604,
  • Mtbp,
  • Mdm2, transformed 3T3 cell double minute p53 binding protein

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For