| Primary Identifier | MGI:107821 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 15117 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables hyaluronan synthase activity. Involved in several processes, including circulatory system development; extracellular matrix assembly; and hyaluronan biosynthetic process. Acts upstream of or within bone morphogenesis and hyaluronan metabolic process. Located in cytoplasmic vesicle and plasma membrane raft. Is active in plasma membrane. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; heart; and skin. Orthologous to human HAS2 (hyaluronan synthase 2). PHENOTYPE: Mice homozygous for a targeted mutation die during midgestation with severe defects in yolk sac and systemic vasculature, including pericardial edema, compaction of the extracellular space, and absence of endocardial cushions and trabeculae. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
