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Protein Coding Gene : Derl1 Der1-like domain family, member 1
Primary Identifier  MGI:1915069 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  67819
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable several functions, including enzyme binding activity; identical protein binding activity; and signal recognition particle binding activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Acts upstream of or within cellular response to unfolded protein. Located in early endosome; endoplasmic reticulum quality control compartment; and late endosome. Is expressed in embryo; gut; pancreas epithelium; yolk sac; and yolk sac endoderm. Orthologous to human DERL1 (derlin 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality during embryogenesis. [provided by MGI curators]
  • synonyms:
  • Der1-like domain family, member 1,
  • Derlin-1,
  • AI195141,
  • expressed sequence AI195141,
  • MGI:2146235,
  • 1110021N07Rik,
  • Derl1,
  • MGI:2145956,
  • RIKEN cDNA 1110021N07 gene,
  • AW551338,
  • expressed sequence AW551338
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Features --> Cross References

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4 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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