| Primary Identifier | MGI:1923520 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 223601 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables MHC class Ib protein binding, via antigen binding activity groove. Involved in several processes, including positive regulation of T cell mediated cytotoxicity; positive regulation of memory T cell activation; and positive regulation of type II interferon production. Located in cilium. Orthologous to human CYRIB (CYFIP related Rac1 interactor B). PHENOTYPE: Homozygous knockout causes increased embryonic death. Conditional knockout in myeloid cells results in increased susceptibility to Salmonella and M. tuberculosis infection-induced morbidity and mortality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
