Primary Identifier | MGI:1313269 | Organism | mouse, laboratory |
Chromosome | 15 | NCBI Gene Number | 18256 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium ion binding activity and structural molecule activity. Involved in otolith mineralization. Located in extracellular matrix. Is expressed in several structures, including cerebellum external granule cell layer; inner ear; and retina nuclear layer. Orthologous to human OC90 (otoconin 90). PHENOTYPE: Mice homozygous for a null allele exhibit reduced, enlarged, and loose otoliths, and thin cupula, saccule, utricle and tectorial membranes. [provided by MGI curators] |