| Primary Identifier | MGI:1859553 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 54562 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in male gonad development. Acts upstream of or within several processes, including epithelial cilium movement involved in extracellular fluid movement; flagellated sperm motility; and outer dynein arm assembly. Located in cytosol. Is active in apical cytoplasm. Used to study primary ciliary dyskinesia 19. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 19. Orthologous to human DNAAF11 (dynein axonemal assembly factor 11). PHENOTYPE: Mice homozygous for a knock-out allele exhibit partial prenatal lethality, variable laterality defects, hydrocephaly, loss of motility in various motile cilia, absence of outer dynein arms in tracheal cilia, and premature death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
