| Primary Identifier | MGI:88067 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 11838 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable mRNA binding activity and structural molecule activity. Involved in long-term memory; regulation of postsynaptic neurotransmitter receptor internalization; and regulation of synaptic plasticity. Acts upstream of or within anterior/posterior pattern specification and endoderm development. Located in dendritic spine; membrane raft; and neuronal ribonucleoprotein granule. Is active in glutamatergic synapse. Is expressed in several structures, including central nervous system; extraembryonic component; metanephros; pancreas mesenchyme; and retina. Orthologous to human ARC (activity regulated cytoskeleton associated protein). PHENOTYPE: Homozygous deletion of this gene results in embryonic lethality around E6.5. Mutations that affect phosphorylation and oligomerization result in learning and memory deficits. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
